孔晓，2019年6月毕业于中科院生态环境研究中心，获环境科学博士学位。现为51cg今日吃瓜热门大瓜劳动卫生与环境卫生学系教师，主要研究方向为肠道菌群和肺部菌群在污染物致病过程中的机制研究。主持山东省自然科学基金项目1项，参与国家自然科学基金项目3项，发表学术论文20余篇。
一、主要研究方向
1.肺部菌群影响聚六亚甲基胍盐致肺纤维化作用机制研究
2.肺肠轴菌群在邻苯二甲酸酯加重过敏性哮喘过程中的机制研究
3.邻苯二甲酸酯呼吸暴露健康风险分析
二、代表性科研成果
1.Xiao Kong, Tomislav Cernava, Yanhui Wang, Decai Jin*. Native fungal community remains resilient during bioremediation of DBP pollution by exogenous Gordonia phthalatica QH-11. Science of the Total Environment 2023, 892, 164532.
2.Xiao Kong, Zhanbing Bai, Tuo Jin, Decai Jin*, Jiangang Pan, Xiangyang Yu, Tomislav Cernava. Arthrobacter is a universal responder to di-n-butyl phthalate (DBP) contamination in soils from various geographical locations. Journal of Hazardous Materials 2022, 422, 126914.
3.Wang Pei#, Kong Xiao#, Chen Hongsong#, Xiao Youlun, Liu Huijun, Li Xiaojuan, Zhang Zhuo, Tan Xinqiu, Wang Diandong, Jin Decai, Deng Ye, Cernava Tomislav. Exploration of Intrinsic Microbial Community Modulators in the Rice Endosphere Indicates a Key Role of Distinct Bacterial Taxa Across Different Cultivars. Frontiers in Microbiology 2021,12, 181.
4.Xiaoxiao Zhu#, Xiao Kong#, Sai Ma, Rui Liu, Xin Li, Shaobo Gao, Dunqiang Ren, Yuxin Zheng*, Jinglong Tang*. TGFβ/Smad mediated the polyhexamethylene guanide areosol-induced irreversible pulmonary fibrosis in subchronic inhalation exposure. Inhalation Toxicology. 2020,32(11-12):419-430.
5.Xiao Kong#, Zhenfei Han#, Xin Tai, Decai Jin, Sen Ai, Xiaoxu Zheng and Zhihui Bai*. Maize (Zea mays L. Sp.) varieties significantly influence bacterial and fungal community in bulk soil, rhizosphere soil and phyllosphere. FEMS Microbiology Ecology 2020, 96, fiaa020.
6.Xiao Kong, Decai Jin*, Xin Tai, Hao Yu, Guilan Duan, Xiulan Yan, Jiangang Pan, Junhua Song, Ye Deng. Bioremediation of dibutyl phthalate in a simulated agricultural ecosystem by Gordonia sp. strain QH-11 and the microbial ecological effects in soil. Science of the Total Environment 2019, 667, 691-700.
7.Xiao Kong, Decai Jin*, Xinxin Wang, Fengsong Zhang, Guilan Duan, Huijun Liu, Minghong Jia, Ye Deng. Dibutyl phthalate contamination remolded the fungal community in agro-environmental system. Chemosphere 2019, 215, 189-198.
8.Xiao Kong, Decai Jin, Shulan Jin, Zhigang Wang, Huaqun Yin, Meiying Xu, Ye Deng*. Responses of bacteria community to dibutyl phthalate (DBP) pollution in a soil-vegetable ecosystem. Journal of Hazardous Materials 2018, 353, 142-150.
三、主要科研项目
1. 肺部菌群通过IL-17B介导促进聚六亚甲基胍盐引起的肺纤维化作用研究，山东省自然科学基金青年项目，15万元，2021-2024，主持.
2. 巨噬细胞源性外泌体ACOD1和ACO2在大气颗粒物暴露致肝脏脂毒性中的作用及机制研究, 国家自然科学基金面上项目, 49万元, 2024-2027, 参与.
3. 拟杆菌和梭菌在DEE暴露致气道重塑中的作用及胞外囊泡（EVs）的调控机制研究, 国家自然科学基金面上项目, 57万元, 2021-2024, 参与.
4. 典型农田土壤微生物群落对邻苯二甲酸酯污染的响应规律、协同降解及根际阻断研究, 国家自然科学基金面上项目, 61万元, 2020-2023, 参与.
四、联系方式
kongxiaozaikeda@163.com
